Choi, Woosuk; Choe, Shawn; Lin, Jingjun; Borchers, Michael T; Kosmider, Beata; Vassallo, Robert; Limper, Andrew H; Lau, Gee W 2020. Exendin-4 restores airway mucus homeostasis through the GLP1R-PKA-PPAR?-FOXA2-phosphatase signaling. Mucosal immunology, 13 4, 637-651
Knoell, Daren L; Smith, Deandra; Bao, Shengying; Sapkota, Muna; Wyatt, Todd A; Zweier, Jay L; Flury, Jennifer; Borchers, Michael T; Knutson, Mitch 2020. Imbalance in zinc homeostasis enhances lung Tissue Loss following cigarette smoke exposure. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 60 , 126483
Liu, Huan; Osterburg, Andrew R; Flury, Jennifer; Swank, Zulma; McGraw, Dennis W; Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Kumar, Ashish; Tazi, Abdellatif; Inoue, Yoshikazu; Hirose, Masaki; McCormack, Francis X; Borchers, Michael T 2020. MAPK mutations and cigarette smoke promote the pathogenesis of pulmonary Langerhans cell histiocytosis. JCI insight, 5 4,
Ochayon, David E; Ali, Ayad; Alarcon, Pablo C; Krishnamurthy, Durga; Kottyan, Leah C; Borchers, Michael T; Waggoner, Stephen N 2020. IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells. Journal of leukocyte biology, 107 4, 663-671
Osterburg, Andrew R; Lach, Laura; Panos, Ralph J; Borchers, Michael T 2020. Unique natural killer cell subpopulations are associated with exacerbation risk in chronic obstructive pulmonary disease. Scientific reports, 10 1, 1238
Rajaram, Sanjeeth; Canaday, Laura M; Ochayon, David E; Rangel, Kelly M; Ali, Ayad; Gyurova, Ivayla E; Krishnamurthy, Durga; Fletcher, Jonathan S; Reighard, Seth D; Cox, Andrew; Weirauch, Matthew T; Kottyan, Leah C; Deshmukh, Hitesh; Zacharias, William J; Borchers, Michael T; Waggoner, Stephen N 2020. The Promise and Peril of Natural Killer Cell Therapies in Pulmonary Infection. Immunity, 52 6, 887-889
Shaw, Brian; Borchers, Michael; Zander, Dani; Gupta, Nishant 2020. Pulmonary Langerhans Cell Histiocytosis. Seminars in respiratory and critical care medicine, 41 2, 269-279
Suzuki, Takuji; McCarthy, Cormac; Carey, Brenna C; Borchers, Michael; Beck, David; Wikenheiser-Brokamp, Kathryn A; Black, Dianna; Chalk, Claudia; Trapnell, Bruce C 2020. Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis. American journal of respiratory cell and molecular biology, 62 1, 87-94
Wellmerling, Jack H; Chang, Sheng-Wei; Kim, Eunsoo; Osman, Wissam H; Boyaka, Prosper N; Borchers, Michael T; Cormet-Boyaka, Estelle 2019. Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice. Respiratory research, 20 1, 200
Liu, Huan; Osterburg, Andrew R; Flury, Jennifer; Huang, Shuo; McCormack, Francis X; Cormier, Stephania A; Borchers, Michael T 2018. NKG2D is Required for Regulation of Lung Pathology and Dendritic Cell Function Following RSV Infection. The Journal of infectious diseases, ,
Osterburg, Andrew R; Lach, Laura; Panos, Ralph J; Borchers, Michael T 2018. Peripheral Blood Natural Killer Cell Phenotypes Associated with Exacerbation Risk in Patients with Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society, 15 Supplement_4, S288-S289
Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kouhei; Li, Na; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Borchers, Michael T; Kopras, Elizabeth J; Plas, David R; Sun, Julia; Franz, David N; Capal, Jamie K; Mays, Maxwell; Sun, Yang; Kwiatkowski, David J; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J 2017. Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells. Molecular cancer research : MCR, 15 10, 1318-1330
Liu, Huan; Jakubzick, Claudia; Osterburg, Andrew R; Nelson, Rebecca L; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T 2017. Dendritic Cell Trafficking and Function in Rare Lung Diseases. American journal of respiratory cell and molecular biology, ,
Osterburg, Andrew R; Nelson, Rebecca L; Yaniv, Benyamin Z; Foot, Rachel; Donica, Walter R F; Nashu, Madison A; Liu, Huan; Wikenheiser-Brokamp, Kathryn A; Moss, Joel; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T 2016. NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline. JCI insight, 1 16, e87270
Wortham, Brian W; Eppert, Bryan L; Flury, Jennifer L; Garcia, Sara Morgado; Donica, Walter R; Osterburg, Andrew; Joyce-Shaikh, Barbara; Cua, Daniel J; Borchers, Michael T 2016. Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies. Journal of immunology (Baltimore, Md. : 1950), 196 8, 3227-31
Borchers, Michael T; Kratzer, Adelheid; Taraseviciene-Stewart, Laimute 2014. Second hand smoke and COPD: lessons from animal studies. Frontiers in physiology, 5 , 144
Hassett, Daniel J; Borchers, Michael T; Panos, Ralph J 2014. Chronic obstructive pulmonary disease (COPD): evaluation from clinical, immunological and bacterial pathogenesis perspectives. Journal of microbiology (Seoul, Korea), 52 3, 211-26
Eppert, Bryan L; Wortham, Brian W; Flury, Jennifer L; Borchers, Michael T 2013. Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950), 190 3, 1331-40
Wortham, Brian W; Eppert, Bryan L; Flury, Jennifer L; Morgado Garcia, Sara; Borchers, Michael T 2013. TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies. PloS one, 8 10, e78735
Wortham, Brian W; Eppert, Bryan L; Motz, Greg T; Flury, Jennifer L; Orozco-Levi, Mauricio; Hoebe, Kasper; Panos, Ralph J; Maxfield, Melissa; Glasser, Stephan W; Senft, Albert P; Raulet, David H; Borchers, Michael T 2012. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950), 188 9, 4468-75
Eppert, Bryan L; Motz, Gregory T; Wortham, Brian W; Flury, Jennifer L; Borchers, Michael T 2010. CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection. Infection and immunity, 78 5, 2099-107
Motz, Gregory T; Eppert, Bryan L; Wesselkamper, Scott C; Flury, Jennifer L; Borchers, Michael T 2010. Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice. American journal of respiratory and critical care medicine, 181 11, 1223-33
Motz, Gregory T; Eppert, Bryan L; Wortham, Brian W; Amos-Kroohs, Robyn M; Flury, Jennifer L; Wesselkamper, Scott C; Borchers, Michael T 2010. Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950), 184 8, 4460-9
Borchers, Michael T; Wesselkamper, Scott C; Curull, Victor; Ramirez-Sarmiento, Alba; Sánchez-Font, Albert; Garcia-Aymerich, Judith; Coronell, Carlos; Lloreta, Josep; Agusti, Alvar G; Gea, Joaquim; Howington, John A; Reed, Michael F; Starnes, Sandra L; Harris, Nathaniel L; Vitucci, Mark; Eppert, Bryan L; Motz, Gregory T; Fogel, Kevin; McGraw, Dennis W; Tichelaar, Jay W; Orozco-Levi, Mauricio 2009. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. The Journal of clinical investigation, 119 3, 636-49
Borchers, Michael T; Wesselkamper, Scott C; Deshmukh, Hitesh; Beckman, Erin; Medvedovic, Mario; Sartor, Maureen; Leikauf, George D 2009. The role of T cells in the regulation of acrolein-induced pulmonary inflammation and epithelial-cell pathology. Research report (Health Effects Institute), 146, 5-29
Caldwell, Charles C; Chen, Yi; Goetzmann, Holly S; Hao, Yonghua; Borchers, Michael T; Hassett, Daniel J; Young, Lisa R; Mavrodi, Dmitri; Thomashow, Linda; Lau, Gee W 2009. Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis. The American journal of pathology, 175 6, 2473-88
Deshmukh, Hitesh S; McLachlan, Anne; Atkinson, Jeffrey J; Hardie, William D; Korfhagen, Thomas R; Dietsch, Maggie; Liu, Yang; Di, Peter Y P; Wesselkamper, Scott C; Borchers, Michael T; Leikauf, George D 2009. Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. American journal of respiratory and critical care medicine, 180 9, 834-45
Borchers, Michael T; Wesselkamper, Scott C; Eppert, Bryan L; Motz, Gregory T; Sartor, Maureen A; Tomlinson, Craig R; Medvedovic, Mario; Tichelaar, Jay W 2008. Nonredundant functions of alphabeta and gammadelta T cells in acrolein-induced pulmonary pathology. Toxicological sciences : an official journal of the Society of Toxicology, 105 1, 188-99
Deshmukh, Hitesh S; Shaver, Colleen; Case, Lisa M; Dietsch, Maggie; Wesselkamper, Scott C; Hardie, William D; Korfhagen, Thomas R; Corradi, Massimo; Nadel, Jay A; Borchers, Michael T; Leikauf, George D 2008. Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production. American journal of respiratory cell and molecular biology, 38 4, 446-54
Motz, Gregory T; Eppert, Bryan L; Sun, Guangyun; Wesselkamper, Scott C; Linke, Michael J; Deka, Ranjan; Borchers, Michael T 2008. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. Journal of immunology (Baltimore, Md. : 1950), 181 11, 8036-43
Wesselkamper, Scott C; Eppert, Bryan L; Motz, Gregory T; Lau, Gee W; Hassett, Daniel J; Borchers, Michael T 2008. NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection. Journal of immunology (Baltimore, Md. : 1950), 181 8, 5481-9
Borchers, Michael T; Wesselkamper, Scott C; Harris, Nathaniel L; Deshmukh, Hitesh; Beckman, Erin; Vitucci, Mark; Tichelaar, Jay W; Leikauf, George D 2007. CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure. Experimental and molecular pathology, 83 3, 301-10
Borchers, Michael T; Harris, Nathaniel L; Wesselkamper, Scott C; Vitucci, Mark; Cosman, David 2006. NKG2D ligands are expressed on stressed human airway epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 291 2, L222-31
Borchers, Michael T; Harris, Nathaniel L; Wesselkamper, Scott C; Zhang, Shiping; Chen, Yi; Young, Lisa; Lau, Gee W 2006. The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa. Infection and immunity, 74 5, 2578-86
McLachlan, Anne; Borchers, Michael; Velayutham, Prakash; Wagner, Michael; Limbach, Patrick A 2006. Characterizing the reproducibility of a protein profiling method for the analysis of mouse bronchoalveolar lavage fluid. Journal of proteome research, 5 11, 3059-65
Wesselkamper, Scott C; McDowell, Susan A; Medvedovic, Mario; Dalton, Timothy P; Deshmukh, Hitesh S; Sartor, Maureen A; Case, Lisa M; Henning, Lisa N; Borchers, Michael T; Tomlinson, Craig R; Prows, Daniel R; Leikauf, George D 2006. The role of metallothionein in the pathogenesis of acute lung injury. American journal of respiratory cell and molecular biology, 34 1, 73-82
Young, Lisa R; Borchers, Michael T; Allen, Holly L; Gibbons, Reta S; McCormack, Francis X 2006. Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome. Journal of immunology (Baltimore, Md. : 1950), 176 7, 4361-8
Deshmukh, Hitesh S; Case, Lisa M; Wesselkamper, Scott C; Borchers, Michael T; Martin, Linda D; Shertzer, Howard G; Nadel, Jay A; Leikauf, George D 2005. Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation. American journal of respiratory and critical care medicine, 171 4, 305-14
Wesselkamper, Scott C; Case, Lisa M; Henning, Lisa N; Borchers, Michael T; Tichelaar, Jay W; Mason, John M; Dragin, Nadine; Medvedovic, Mario; Sartor, Maureen A; Tomlinson, Craig R; Leikauf, George D 2005. Gene expression changes during the development of acute lung injury: role of transforming growth factor beta. American journal of respiratory and critical care medicine, 172 11, 1399-411
Leikauf, George D; Borchers, Michael T; Prows, Daniel R; Simpson, Leigh G 2002. Mucin apoprotein expression in COPD. Chest, 121 5 Suppl, 166S-182S
Borchers, M T; Carty, M P; Leikauf, G D 1999. Regulation of human airway mucins by acrolein and inflammatory mediators. The American journal of physiology, 276 4 Pt 1, L549-55
Borchers, M T; Wesselkamper, S; Wert, S E; Shapiro, S D; Leikauf, G D 1999. Monocyte inflammation augments acrolein-induced Muc5ac expression in mouse lung. The American journal of physiology, 277 3 Pt 1, L489-97
Borchers, M T; Wert, S E; Leikauf, G D 1998. Acrolein-induced MUC5ac expression in rat airways. The American journal of physiology, 274 4 Pt 1, L573-81
Balasubramaniam, A; Ujhelyi, M; Borchers, M; Huang, Y; Zhai, W; Zhou, Y; Johnson, M; Sheriff, S; Fischer, J E 1996. Antagonistic properties of centrally truncated analogs of [D-Trp(32)]NPY. Journal of medicinal chemistry, 39 5, 1142-7
Chance, W T; Balasubramaniam, A; Borchers, M; Fischer, J E 1995. Refractory hypothalamic adenylate cyclase in anorectic tumor-bearing rats: implications for NPY-induced feeding. Brain research, 691 1-2, 180-4
Norman, A B; Borchers, M T; Wachendorf, T J; Price, A L; Sanberg, P R 1989. Loss of D1 and D2 dopamine receptors and muscarinic cholinergic receptors in rat brain following in vitro polytron homogenization. Brain research bulletin, 22 4, 633-6