Prasad, Vikram; Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Huang, Wei; Wang, Yigang; Wieczorek, David W; Shull, Gary E 2015. SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure. BioMed research international, 2015 , 251598
Tarigopula, Madhusudhan; Davis, Robert T; Mungai, Paul T; Ryba, David M; Wieczorek, David F; Cowan, Conrad L; Violin, Jonathan D; Wolska, Beata M; Solaro, R John 2015. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular research, 107 2, 226-34
Wilder, Tanganyika; Ryba, David M; Wieczorek, David F; Wolska, Beata M; Solaro, R John 2015. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. American journal of physiology. Heart and circulatory physiology, 309 10, H1720-30
Prasad, Vikram; Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Jiang, Min; Gao, Xu; Rubinstein, Jack; Wieczorek, David F; Shull, Gary E 2014. Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. Journal of molecular and cellular cardiology, 77 , 53-63
Rajan S, Pena J, Jegga A, Aronow B, Wolska B, and Wieczorek DF. 2013. Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescues by a phospholamban knockout Physiological Genomics, ,
Rajan, Sudarsan; Pena, James R; Jegga, Anil G; Aronow, Bruce J; Wolska, Beata M; Wieczorek, David F 2013. Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiological genomics, 45 17, 764-73
Schulz E and Wieczorek DF 2013. Tropomyosin de-phosphorylation in the heart: what are the consequences J Muscle Res Cell Motil, ,
Schulz, Emily M; Wieczorek, David F 2013. Tropomyosin de-phosphorylation in the heart: what are the consequences? Journal of muscle research and cell motility, 34 3-4, 239-46
Schulz, Emily M; Wilder, Tanganyika; Chowdhury, Shamim A K; Sheikh, Hajer N; Wolska, Beata M; Solaro, R John; Wieczorek, David F 2013. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of biological chemistry, 288 40, 28925-35
Schulz, Emily M; Correll, Richard N; Sheikh, Hajer N; Lofrano-Alves, Marcos S; Engel, Patti L; Newman, Gilbert; Schultz, Jo El J; Molkentin, Jeffery D; Wolska, Beata M; Solaro, R John; Wieczorek, David F 2012. Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy The Journal of biological chemistry, 287 , 44478-44489
Al Moamen, Nabeel J; Prasad, Vikram; Bodi, Ilona; Miller, Marian L; Neiman, Michelle L; Lasko, Valerie M; Alper, Seth L; Wieczorek, David F; Lorenz, John N; Shull, Gary E 2011. Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. Journal of molecular and cellular cardiology, 50 1, 137-46
Jagatheesan, Ganapathy; Rajan, Sudarsan; Ahmed, Rafeeq P H; Petrashevskaya, Natalia; Boivin, Greg; Arteaga, Grace M; Tae, Hyun-Jin; Liggett, Stephen B; Solaro, R John; Wieczorek, David F 2010. Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity. Journal of muscle research and cell motility, 31 3, 227-39
Jagatheesan, Ganapathy; Rajan, Sudarsan; Wieczorek, David F 2010. Investigations into tropomyosin function using mouse models. Journal of molecular and cellular cardiology, 48 5, 893-8
Rajan, Sudarsan; Jagatheesan, Ganapathy; Karam, Chehade N; Alves, Marco L; Bodi, Ilona; Schwartz, Arnold; Bulcao, Christian F; D'Souza, Karen M; Akhter, Shahab A; Boivin, Greg P; Dube, Dipak K; Petrashevskaya, Natalia; Herr, Andrew B; Hullin, Roger; Liggett, Stephen B; Wolska, Beata M; Solaro, R John; Wieczorek, David F 2010. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation, 121 3, 410-8
Jagatheesan, Ganapathy; Rajan, Sudarsan; Schulz, Emily M; Ahmed, Rafeeq P H; Petrashevskaya, Natalia; Schwartz, Arnold; Boivin, Greg P; Arteaga, Grace M; Wang, Tao; Wang, Yi-Gang; Ashraf, Muhammad; Liggett, Stephen B; Lorenz, John; Solaro, R John; Wieczorek, David F 2009. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American journal of physiology. Heart and circulatory physiology, 297 1, H181-90
Wieczorek, David F; Jagatheesan, Ganapathy; Rajan, Sudarsan 2008. The role of tropomyosin in heart disease. Advances in experimental medicine and biology, 644 , 132-42
Jagatheesan, Ganapathy; Rajan, Sudarsan; Petrashevskaya, Natalia; Schwartz, Arnold; Boivin, Greg; Arteaga, Grace M; Solaro, R John; Liggett, Stephen B; Wieczorek, David F 2007. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. American journal of physiology. Heart and circulatory physiology, 293 2, H949-58
Rajan, Sudarsan; Ahmed, Rafeeq P H; Jagatheesan, Ganapathy; Petrashevskaya, Natalia; Boivin, Greg P; Urboniene, Dalia; Arteaga, Grace M; Wolska, Beata M; Solaro, R John; Liggett, Stephen B; Wieczorek, David F 2007. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity. Circulation research, 101 2, 205-14
Rajan, Sudarsan; Williams, Sarah S; Jagatheesan, Ganapathy; Ahmed, Rafeeq P H; Fuller-Bicer, Geraldine; Schwartz, Arnold; Aronow, Bruce J; Wieczorek, David F 2006. Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy. Physiological genomics, 27 3, 309-17
Dhoke, M A; Ladha, P J; Boerio, F J; Lessard, L B; Malinowska, D H; Cuppoletti, J; Wieczorek, D S 2005. Porous membranes for reconstitution of ion channels. Biochimica et biophysica acta, 1716 2, 117-25
Jagatheesan, Ganapathy; Rajan, Sudarsan; Petrashevskaya, Natalia; Schwartz, Arnold; Boivin, Greg; Arteaga, Grace; de Tombe, Pieter P; Solaro, R John; Wieczorek, David F 2004. Physiological significance of troponin T binding domains in striated muscle tropomyosin. American journal of physiology. Heart and circulatory physiology, 287 4, H1484-94
Jagatheesan, Ganapathy; Rajan, Sudarsan; Petrashevskaya, Natalia; Schwartz, Arnold; Boivin, Greg; Vahebi, Susan; DeTombe, Pieter; Solaro, R John; Labitzke, Erin; Hilliard, George; Wieczorek, David F 2003. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin. The Journal of biological chemistry, 278 25, 23204-11
Prabhakar, Rethinasamy; Petrashevskaya, Natalia; Schwartz, Arnold; Aronow, Bruce; Boivin, Greg P; Molkentin, Jeffery D; Wieczorek, David F 2003. A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation. Molecular and cellular biochemistry, 251 1-2, 33-42
Pieples, Kathy; Arteaga, Grace; Solaro, R John; Grupp, Ingrid; Lorenz, John N; Boivin, Greg P; Jagatheesan, Ganapathy; Labitzke, Erin; DeTombe, Pieter P; Konhilas, John P; Irving, Thomas C; Wieczorek, David F 2002. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American journal of physiology. Heart and circulatory physiology, 283 4, H1344-53
Prabhakar, R; Boivin, G P; Grupp, I L; Hoit, B; Arteaga, G; Solaro, J R; Wieczorek, D F 2001. A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice. Journal of molecular and cellular cardiology, 33 10, 1815-28
Pieples, K; Wieczorek, D F 2000. Tropomyosin 3 increases striated muscle isoform diversity. Biochemistry, 39 28, 8291-7
Muthuchamy, M; Pieples, K; Rethinasamy, P; Hoit, B; Grupp, I L; Boivin, G P; Wolska, B; Evans, C; Solaro, R J; Wieczorek, D F 1999. Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction. Circulation research, 85 1, 47-56
Prabhakar, R; Boivin, G P; Hoit, B; Wieczorek, D F 1999. Rescue of high expression beta-tropomyosin transgenic mice by 5-propyl-2-thiouracil. Regulating the alpha-myosin heavy chain promoter. The Journal of biological chemistry, 274 41, 29558-63
Muthuchamy, M; Boivin, G P; Grupp, I L; Wieczorek, D F 1998. Beta-tropomyosin overexpression induces severe cardiac abnormalities. Journal of molecular and cellular cardiology, 30 8, 1545-57
Sussman, M A; Lim, H W; Gude, N; Taigen, T; Olson, E N; Robbins, J; Colbert, M C; Gualberto, A; Wieczorek, D F; Molkentin, J D 1998. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.), 281 5383, 1690-3
Muthuchamy, M; Rethinasamy, P; Wieczorek, D F 1997. Tropomyosin structure and function new insights. Trends in cardiovascular medicine, 7 4, 124-8
Muthuchamy, M; Grupp, I L; Grupp, G; O'Toole, B A; Kier, A B; Boivin, G P; Neumann, J; Wieczorek, D F 1995. Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart. The Journal of biological chemistry, 270 51, 30593-603
Muthuchamy, M; Pajak, L; Howles, P; Doetschman, T; Wieczorek, D F 1993. Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos. Molecular and cellular biology, 13 6, 3311-23
Diebold, R J; Koch, W J; Ellinor, P T; Wang, J J; Muthuchamy, M; Wieczorek, D F; Schwartz, A 1992. Mutually exclusive exon splicing of the cardiac calcium channel alpha 1 subunit gene generates developmentally regulated isoforms in the rat heart. Proceedings of the National Academy of Sciences of the United States of America, 89 4, 1497-501
Muthuchamy, M; Pajak, L; Wieczorek, D F 1992. Induction of endogenous myosin light chain 1 and cardiac alpha-actin expression in L6E9 cells by MyoD1. The Journal of biological chemistry, 267 26, 18728-34
Hasselgren, P O; Tricoli, J V; Wieczorek, D; Steigerwald, K A; Angerås, U; Hall-Angerås, M; Fischer, J E 1991. Reduced levels of mRNA for myofibrillar proteins in skeletal muscle from septic rats. Life sciences, 49 10, 753-60
Pajak, L; Mariappan, M; Wieczorek, D F 1991. Reprogramming of myosin light chain 1/3 expression in muscle heterokaryons. Developmental biology, 145 1, 28-39
Wieczorek, D F; Hughes, S R 1991. Developmentally regulated cDNA expressed exclusively in neural tissue. Brain research. Molecular brain research, 10 1, 33-41
Wieczorek, D F 1988. Regulation of alternatively spliced alpha-tropomyosin gene expression by nerve extract. The Journal of biological chemistry, 263 21, 10456-63