Publications

2023

• Pathak, B.; Lange, T.E.; Lampe, K.; Hollander, E.; Oria, M.; Murphy, K.P.; Salomonis, N.; Sertorio, M.; Oria, M. Development of a Single-Neurosphere Culture to Assess Radiation Toxicity and Pre-Clinical Cancer Combination Therapy Safety. Cancers 2023, 15, 4916. https://doi.org/10.3390/cancers15204916

• Siddiqui NA, Ventrola AJ, Hartman AR, Konare T, Kamble NS, Thomas SC, Madaan T, Kharofa J, Sertorio MG, Kotagiri N. An Engineered Probiotic Platform for Cancer Epitope-Independent Targeted Radionuclide Therapy of Solid Tumors. Adv Healthc Mater. 2023 Mar 13:e2202870. doi: 10.1002/adhm.202202870. Epub ahead of print. PMID: 36913614.

• Korns J, McCauley S, Lehn M, Takiar V, Sertorio M, Lamba M. Varied Photon Radiation Sources Produce Differences in Cellular Response. Radiat Res. 2023 Apr 1;199(4):422-428. doi: 10.1667/RADE-22-00210.1. PMID: 37039678.

• Mascia A, McCauley S, Speth J, Nunez SA, Boivin G, Vilalta M, Sharma RA, Perentesis JP, Sertorio M. Impact of Multiple Beams on the FLASH Effect in Soft Tissue and Skin in Mice. Int J Radiat Oncol Biol Phys. 2023 Aug 2:S0360-3016(23)07678-2. doi: 10.1016/j.ijrobp.2023.07.024. Epub ahead of print. PMID: 37541394.

2022

• Chihanga, T., S. Vicente-Muñoz, S. Ruiz-Torres, B. Pal, M. Sertorio, P. R. Andreassen, R. Khoury, P. Mehta, S. M. Davies, A. N. Lane, L. E. Romick-Rosendale, and S. I. Wells. "Head and Neck Cancer Susceptibility and Metabolism in Fanconi Anemia." Cancers (Basel) 14, no. 8 (Apr 18 2022). http://dx.doi.org/10.3390/cancers14082040.

• Dubey, P., M. Sertorio, and V. Takiar. "Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy." Cancers (Basel) 14, no. 3 (Jan 20 2022). http://dx.doi.org/10.3390/cancers14030514.
  

• Williams MT, Sugimoto C, Regan SL, Pitzer EM, Fritz AL, Sertorio M, Mascia AE, Vatner RE, Perentesis JP, Vorhees CV. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. PLoS One. 2022 Sep 16;17(9):e0274007. doi: 10.1371/journal.pone.0274007. PMID: 36112695; PMCID: PMC9481014

• Mascia AE, Daugherty EC, Zhang Y, Lee E, Xiao Z, Sertorio M, Woo J, Backus LR, McDonald JM, McCann C, Russell K, Levine L, Sharma RA, Khuntia D, Bradley JD, Simone CB 2nd, Perentesis JP, Breneman JC. Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial. JAMA Oncol. 2022 Oct 23:e225843. doi: 10.1001/jamaoncol.2022.5843. Epub ahead of print. PMID: 36273324; PMCID: PMC9589460.

• Daugherty EC, Mascia AE, Zhang Y, Lee E, Xiao Z, Sertorio M, Woo J, McCann C, Russell KJ, Levine LL, Sharma RA, Khuntia D, Bradley J, Simone Nd CB, Perentesis JP, Breneman JC. FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study. JMIR Res Protoc. 2022 Oct 4. doi: 10.2196/41812. Epub ahead of print. PMID: 36206189.

2021

• Cunningham S, McCauley S, Vairamani K, Speth J, Girdhani S, Abel E, Sharma RA, Perentesis JP, Wells SI, Mascia A, Sertorio M. FLASH Proton Pencil Beam Scanning Irradiation Minimizes Radiation-Induced Leg Contracture and Skin Toxicity in Mice. Cancers (Basel). 2021 Mar 1;13(5):1012. doi: 10.3390/cancers13051012. PMID: 33804336; PMCID: PMC7957631.

• Ruiz-Torres, S., M. G. Brusadelli, D. P. Witte, K. A. Wikenheiser-Brokamp, S. Sauter, A. S. Nelson, M.Sertorio, T. M. Chlon, A. Lane, P. A. Mehta, K. C. Myers, M. C. Bedard, B. Pal, D. M. Supp, P. F. Lambert, K. Komurov, M. B. Kovacic, S. M. Davies, and S. I. Wells. "Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin." Cell Stem Cell 28, no. 3 (Mar 4 2021): 424-35.e6. http://dx.doi.org/10.1016/j.stem.2020.10.012,

• Sertorio, M., A. Nowrouzi, M. Akbarpour, K. Chetal, N. Salomonis, S. Brons, A. Mascia, D. Ionascu, S. McCauley, T. Kupneski, A. Köthe, J. Debus, J. P. Perentesis, A. Abdollahi, Y. Zheng, and S. I. Wells. "Differential Transcriptome Response to Proton Versus X-Ray Radiation Reveals Novel Candidate Targets for Combinatorial Pt Therapy in Lymphoma." Radiother Oncol 155 (Feb 2021): 293-303. http://dx.doi.org/10.1016/j.radonc.2020.10.024.

2020

• Williams MT, Sugimoto C, Regan SL, Pitzer EM, Fritz AL, Mascia AE, Sertorio M, Vatner RE, Perentesis JP, Vorhees CV. Whole brain proton irradiation in adult Sprague Dawley rats produces dose dependent and non-dependent cognitive, behavioral, and dopaminergic effects. Sci Rep. 2020 Dec 9;10(1):21584. doi: 10.1038/s41598-020-78128-1. PMID: 33299021; PMCID: PMC7726106.

• Ruiz-Torres S, Brusadelli MG, Witte DP, Wikenheiser-Brokamp KA, Sauter S, Nelson AS, Sertorio M, Chlon TM, Lane A, Mehta PA, Myers KC, Bedard MC, Pal B, Supp DM, Lambert PF, Komurov K, Kovacic MB, Davies SM, Wells SI. Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin. Cell Stem Cell. 2021 Mar 4;28(3):424-435.e6. doi: 10.1016/j.stem.2020.10.012. Epub 2020 Nov 23. PMID: 33232662; PMCID: PMC7935766.

• Sertorio M, Nowrouzi A, Akbarpour M, Chetal K, Salomonis N, Brons S, Mascia A, Ionascu D, McCauley S, Kupneski T, Köthe A, Debus J, Perentesis JP, Abdollahi A, Zheng Y, Wells SI. Differential transcriptome response to proton versus X-ray radiation reveals novel candidate targets for combinatorial PT therapy in lymphoma. Radiother Oncol. 2021 Feb;155:293-303. doi: 10.1016/j.radonc.2020.10.024. Epub 2020 Oct 20. PMID: 33096164.

• Pease NA, Shephard MS, Sertorio M, Waltz SE, Vinnedge LMP. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers (Basel). 2020 Jul 17;12(7):1936. doi: 10.3390/cancers12071936. PMID: 32708944; PMCID: PMC7409092.

• Nowrouzi A, Sertorio MG, Akbarpour M, Knoll M, Krunic D, Kuhar M, Schwager C, Brons S, Debus J, Wells SI, Wells JM, Abdollahi A. Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids. Cancers (Basel). 2020 Feb 18;12(2):469. doi: 10.3390/cancers12020469. PMID: 32085439; PMCID: PMC7072449.

2018

• Sertorio M, Perentesis JP, Vatner RE, Mascia AE, Zheng Y, Wells SI. Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy. Int J Part Ther. 2018 Summer;5(1):40-48. doi: 10.14338/IJPT-18-00023.1. Epub 2018 Sep 21. PMID: 31773019; PMCID: PMC6871586.

• Serrano-Lopez J, Nattamai K, Pease NA, Shephard MS, Wellendorf AM, Sertorio M, Smith EA, Geiger H, Wells SI, Cancelas JA, Privette Vinnedge LM. Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Exp Hematol. 2018 Mar;59:40-50.e3. doi: 10.1016/j.exphem.2017.12.009. Epub 2017 Dec 27. PMID: 29288703; PMCID: PMC5844846.

2017

• Sertorio M, Du W, Amarachintha S, Wilson A, Pang Q. In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis. Stem Cell Reports. 2017 May 9;8(5):1242-1255. doi: 10.1016/j.stemcr.2017.03.008. Epub 2017 Apr 13. PMID: 28416286; PMCID: PMC5425620.

2016

• Sertorio M, Amarachintha S, Wilson A, Pang Q. Loss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt Signaling Pathway. J Immunol. 2016 Apr 1;196(7):2986-94. doi: 10.4049/jimmunol.1501056. Epub 2016 Feb 19. PMID: 26895835; PMCID: PMC4799755.

• Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, Li J, Oyegue S, Arnaud V, Luo X, Daujat-Chavanieu M, Mariani O, Sastre X, Dombey AM, He H, Li Y, Dessein A. Correction: FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly. PLoS Negl Trop Dis. 2016 Feb 5;10(2):e0004454. doi: 10.1371/journal.pntd.0004454. Erratum for: PLoS Negl Trop Dis. 2016 Jan;10(1):e0004306. Chavanieu, Martine [corrected to Daujat-Chavanieu, Martine]. PMID: 26849557; PMCID: PMC4743961.

• Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, Li J, Oyegue S, Arnaud V, Luo X, Daujat-Chavanieu M, Mariani O, Sastre X, Dombey AM, He H, Li Y, Dessein A. FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly. PLoS Negl Trop Dis. 2016 Jan 5;10(1):e0004306. doi: 10.1371/journal.pntd.0004306. Erratum in: PLoS Negl Trop Dis. 2016 Feb;10(2):e0004454. Chavanieu, Martine [corrected to Daujat-Chavanieu, Martine]. PMID: 26731721; PMCID: PMC4701139.

2015

• Amarachintha S, Sertorio M, Wilson A, Li X, Pang Q. Fanconi Anemia Mesenchymal Stromal Cells-Derived Glycerophospholipids Skew Hematopoietic Stem Cell Differentiation Through Toll-Like Receptor Signaling. Stem Cells. 2015 Nov;33(11):3382-96. doi: 10.1002/stem.2100. Epub 2015 Jul 24. PMID: 26212365; PMCID: PMC4618082.

• Li X, Zhang T, Wilson A, Amarachintha S, Sertorio M, Pang Q. Transcriptional profiling of Foxo3a and Fancd2 regulated genes in mouse hematopoietic stem cells. Genom Data. 2015 Jun 1;4:148-149. doi: 10.1016/j.gdata.2015.04.011. PMID: 25984447; PMCID: PMC4430722.

• Sertorio M, Carmo RF, Cabantous S, Vasconcelos L, Pereira LB, Moura P, Dessein A. Reply: To PMID 25476703. Hepatology. 2015 Dec;62(6):1920. doi: 10.1002/hep.27855. Epub 2015 Jun 19. PMID: 25907639.

• Sertorio M, Hou X, Carmo RF, Dessein H, Cabantous S, Abdelwahed M, Romano A, Albuquerque F, Vasconcelos L, Carmo T, Li J, Varoquaux A, Arnaud V, Oliveira P, Hamdoun A, He H, Adbelmaboud S, Mergani A, Zhou J, Monis A, Pereira LB, Halfon P, Bourlière M, Parana R, Dos Reis M, Gonnelli D, Moura P, Elwali NE, Argiro L, Li Y, Dessein A. IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections. Hepatology. 2015 Apr;61(4):1321-31. doi: 10.1002/hep.27629. Epub 2015 Mar 10. PMID: 25476703.

Prior to 2015

• Berry A, Deymier C, Sertorio M, Witkowski B, Benoit-Vical F. Pfs 16 pivotal role in Plasmodium falciparum gametocytogenesis: a potential antiplasmodial drug target. Exp Parasitol. 2009 Feb;121(2):189-92. doi: 10.1016/j.exppara.2008.10.010. Epub 2008 Nov 5. PMID: 19014941.

• Salhi A, Rodrigues V Jr, Santoro F, Dessein H, Romano A, Castellano LR, Sertorio M, Rafati S, Chevillard C, Prata A, Alcaïs A, Argiro L, Dessein A. Immunological and genetic evidence for a crucial role of IL-10 in cutaneous lesions in humans infected with Leishmania braziliensis. J Immunol. 2008 May 1;180(9):6139-48. doi: 10.4049/jimmunol.180.9.6139. PMID: 18424735.